Buy Cryogenic Containers: 5 Mistakes to Avoid

by Cryonos Project on October 03, 2025
Cryogenic Containers

A cryogenic container is an essential element in research, medicine, and industry when it comes to the safe storage and transportation of liquid nitrogen or cryopreserved samples. However, purchasing a cryogenic container involves navigating a wide range of options – as well as potential pitfalls. Choosing the wrong container can not only be costly but may also endanger samples and significantly disrupt operations. In this article, we highlight the five most common mistakes made when buying a cryogenic container and provide practical advice on how to avoid them.

1. Choosing the Wrong Capacity

A common mistake made by laboratories and clinics is underestimating the required capacity. A container that is too small will require frequent refilling of liquid nitrogen, while an oversized container results in unnecessary expenses.


Practical example:
An IVF center initially opted for a 20-liter container for cryopreservation. Within just a few months, the capacity proved insufficient, requiring additional transfers. With needs-based planning, the center could have saved costs in the long run.


Tip:
Carefully assess your current and future sample volumes. Consider growth projections and storage duration, and seek professional guidance before making a purchase.

2. Storage Containers and Transport Containers Used Incorrectly

A particularly critical error is using the wrong container for the wrong purpose. Storage containers are designed for stable, long-term preservation of samples, while transport containers are specifically engineered to ensure safety, protection, and regulatory compliance during shipment. Using a storage container for transport risks both sample loss and legal issues.


How to avoid this mistake:

  • Use storage containers exclusively in stationary setups.
  • For shipping, only use certified transport containers.
  • Follow ADR hazardous materials regulations during transport.

3. Poor Handling Due to Incorrect Neck Opening Size

An often-overlooked yet crucial factor when purchasing a cryogenic container is the dimension of the neck opening. Neck size impacts not only ease of handling but also the efficiency of nitrogen consumption.


  • Neck opening too large:
    Provides convenient and fast access to samples but significantly increases nitrogen evaporation. This means more frequent refilling and higher operating costs.
  • Neck opening too small:
    Minimizes nitrogen loss and extends holding time but makes everyday handling more difficult – especially when large volumes of samples are frequently accessed. This can slow down workflows in laboratories or clinics and compromise operator safety.

Practical recommendation:
Before purchasing, analyze how frequently and in what quantities you will access your samples. For high-throughput applications (e.g., IVF labs or biomedical research facilities), a medium to large neck opening combined with efficient insulation design is advisable. For long-term storage with infrequent access, a smaller neck opening is the better option to reduce nitrogen losses.

Cryogenic Containers, Neck Opening
Cryogenic Containers, Neck Opening
Cryogenic Containers, Neck Opening

4. Lack of Compatibility with Sample Holders

Not every cryogenic container is suitable for every sample format. The internal design must be precisely aligned with your storage systems. Otherwise, samples may be stored insecurely, poorly organized, or may not fit into the container at all—posing risks to sample integrity and workflow efficiency.


Common sample formats and requirements:

  • Straws (0.25–0.5 ml): Typically stored in canisters
  • Cryovials (1–5 ml): Usually stored in racks with cryoboxes
  • Blood bags: Stored in specialized blood bag racks

Practical Tip:
Before purchasing a cryogenic container, determine which sample formats you intend to store—and choose a model specifically designed to accommodate them.

5. Neglecting Service and Spare Parts

A cryogenic container is a long-term investment. Focusing only on the purchase price often leads buyers to overlook the importance of service, maintenance, and spare parts availability.


Recommendation:
Choose established brands and reputable suppliers that offer service, warranty, and guaranteed spare part availability.


Conclusion: Buying the Right Cryogenic Container – Safely and Efficiently

To operate safely, efficiently, and cost-effectively, it is essential to avoid the mistakes outlined above. From selecting the right capacity and neck size to ensuring compatibility and service support, investing in quality and expert advice pays off.


👉 Explore our selection of cryogenic containers in our shop and get tailored advice from our experts! Or use our Product Finder to identify the right model in just a few clicks – based on your application, sample type, sample volume, and required holding time.

FAQ: Common Questions When Buying Cryogenic Containers

1. How do I choose the right container for my application?

It depends on factors such as sample type, volume, storage duration, and frequency of access. Important considerations include neck size, capacity, and compatibility with your sample storage system.

2. Can storage containers be used for transport?

No. Standard storage containers are unsuitable for shipping. Use only certified transport containers designed for safe handling and compliance with regulations.

3. How long does liquid nitrogen last in a cryogenic container?

Holding time varies depending on the model and size, ranging from a few days to several weeks.

4. What regulations apply to the transport of cryogenic containers?

Transport falls under ADR hazardous goods regulations. Only certified transport containers may be used.

5. Is it safe to buy a used cryogenic container?

Only if the vacuum has been tested and full documentation is provided. In most cases, a new unit with warranty is the safer investment.

Disclaimer

The information provided in this blog post is intended solely for general informational purposes. It does not constitute legal, medical, technical, or safety-related advice and cannot replace personalized professional consultation.

Although we compile the content with the utmost care, we make no representations or warranties regarding the completeness, accuracy, or timeliness of the information provided. Use of the information is at your own risk.

We expressly disclaim any liability for damages, whether direct or indirect, arising from the use of or reliance upon the information described in this blog.

Please always adhere to applicable laws, regulations, standards, and safety guidelines. For specific questions or decisions, always consult qualified professionals.

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